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inhalation anaesthetic การใช้

ประโยค

  1. Like all potent inhalation anaesthetic agents it is a known trigger of malignant hyperthermia.
  2. Amitriptyline increases the CNS depressant action, but not the anticonvulsant action of barbiturates; therefore, an inhalation anaesthetic or diazepam is recommended for control of convulsions . protein binding with amitriptyline.
  3. Mice in which the TASK-3 gene has been deleted have reduced sensitivity to inhalation anaesthetics, exaggerated nocturnal activity and cognitive deficits as well as significantly increased appetite and weight gain.
  4. Highlighting the impact of inhalation anaesthetic metabolism and toxicity in the era 1970-1990, his key paper with Richard Mazze on methoxyflurane nephrotoxicity was also in the top 100 most cited papers over the past 60 years.
  5. Anaesthesia related research themes have encompassed a very broad range of themes : metabolism and renal toxicity of inhalation anaesthetics, antibiotics and NSAIDs  providing the first evidence with Richard Mazze in 1974 of organ toxicity of a drug metabolite ( published in Journal of Pharmacology & Experimental Therapeutics ) as well as multiple related papers; metabolism and hepatoxicity of halothane, utilizing basic and clinical studies to demonstrate both acute metabolite initiated toxicity and delayed metabolite-immune mediated hepatoxicity; toxicity of chronic inhalation of halogenated hydrocarbons; intravenous sedatives and anaesthetics pharmacokinetics, pharmacodynamics and side effects; local anaesthetic pharmacology; epidural and intrathecal neural blockade, pharmacologyy and physiology.

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